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Results: Coeliac patients showed a higher total plasma homocysteine level than the general population, indicative of a poor vitamin status. In accordance, the plasma levels of folate and pyridoxal 5″-phosphate (active form of vitamin B-6) were low in 37% and 20%, respectively, and accounted for 33% of the variation of the total plasma homocysteine level (P < 0.008). The mean daily intakes of folate and vitamin B-12, but not of vitamin B-6, were significantly lower in coeliac patients than in controls. Conclusions: Half of the adult coeliac patients carefully treated with a gluten-free diet for several years showed signs of a poor vitamin status. This may have clinical implications considering the linkage between vitamin deficiency, elevated total plasma homocysteine levels and cardiovascular disease. The results may suggest that, when following up adults with coeliac disease, the vitamin status should be reviewed.
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19 Responses
My dr has me on 35,000 units of b12/folate sublinigual(sp)(my choice) supplements because injections were not effective plus my limbs would go numb after the injection. I suffer from horrible stomach pain, bloat,inflammation, neuropathy and organ problems, joint pain etc etc. To date my b12 levels are still below 220. I take 35,000 + units of Vitamin D3 a week, those levels seem to be holding slightly above low. I am not sure at this point what I can do get my levels up where they should be, I eat foods that contain b vitamins, and still I can’t retain b12. My dr wont test any other deficiences because my CBC comes back fine. I have discussed with her your research and it goes in one ear out the other–she wants to see documented support of the findings. Trying to find another dr in my area who is up to date on Gluten sensitivity and celiac disease is like looking for a needle in a vey large haystack, I’ve gotten where I am now with the dr I have. How do you get your dr to take you serious about the damage Gluten sensitivity/Celiac Disease can do?
I had to get genetic DNA testing which proved that my B12 would not absorb into the cells. Labs showed it to be normal in the blood. I now take 3 types of B12 methyl, hydroxyl and Adeno in sublingual forms. The 3 together are clearing the brain fog and helping energy levels. Genetic testing was necessary. I have spent $10,000 getting no proper answer until now.
I agree with the genetic testing. I spent a fortune on doctor after doctor till going tho a genetic nutritionist was suggested. I go to Bob miller Tree of life in pa. With him changing my supplements taking me off folate and vita c I am doing better
I use injectable B12 that has no preservatives, it’s the only one that my body will metabolize.
Too bad there’s no indication here as to a minimum level or suggested level of vitamin C supplementation. I realize individual needs could vary but at least give us a benchmark from which to work . . . .
Reginald,
Start with 2 grams/day. I recommend working up to 5 grams/day if well tolerated.
For the maximum Vitamin C, you could go to bowel tolerance (where you get diarrhea) and then back down.
Go slowly so you don’t overdo it.
I, have tried the B12 injections also, but after the third one, my entire face and neck broke out horribly, and this lasted for a few months. I also eat many foods with B vitamins, but don’t seem to be able to bring the numbers up.
To tain any benefit from magnesium, b vitamins and calcium you first need to have a good vita December level. Unless you live at the equator you likely do not. Simple blood test to check. Start with 5000 units of liquid vita D. Capsule or liquid only. Omit all grains and sugar.
I’ve used Premiere Research Labs’ Max B Stress and was able to raise my B12 level from around 230 to the mid 600’s in about 4 months. Interesting info on Vitamin C…my bet is that most Americans have a bit of subclinical scurvy to deal with!
I have eaten normally my whole life not sure if I have celiac disease or not. It seems if I eat bread, beer, cakes, pastas,candies etc that I get sick as a dog. I do not understand being gluten free or what gluten free foods are. Even lists of gluten free foods on line are not entirely true. Help?
An average GP only know so much of the field he is in. The do not research further on anything unless they have these symptoms with close family members or themselves. It is very seldom found that our doctors knows anything about glute/wheat sensitivity. My doctor’s wife and two children suffer from it and that is why he could diagnose me, but he still is under the impression that I can eat oats, buckwheat, rice and corn!!
If you have Hashimoto’s,an autoimmune disease that effects the thyroid,you probably shouldn’t take iodine. For me,iodine is more inflammatory than gluten(although I don’t eat either),and harder to know if it’s in my food,especially when I eat out.
Penny,
find yourself a functional or integrative physician to handle these issues. National associations have websites, showing their locations in your general area. If no luck, then visit Dr Hymen’s website (known for all food allergies), and find a link or information about national associations. Common sense would be to go off of all gluten as a test: if you feel better in a week or so, you are on the right path! Eventually, you may not require massive doses of vitamins. Hope this helps!
I went wheat free about 6 months ago which cured several health issues including acid reflux, arthritis pain, low energy, etc. I’m feeling 20 years younger. I had trouble with B-12 levels, and I found that placing a drop of water on a 5 mg sublingual tablet to dissolve it and then placing it in each nostril every day, (using my pinky), took care of getting the B-12 I had lacked. More efficient absorption than under the tongue. Much less expensive, too, as it stretched the tablet over about 3 or 4 days. Good luck.
Im a gluten sensitive….im already avoiding those gluten food but still having edema…please help me…i know my protein is low. thank you
I would think that the missing link here is fermented foods. Fermented foods such as sauerkraut, kimchi, and kombucha actually help you digest and break down your foods as well as aiding in nutrient absorption. I cured myself of a 36 year lactose intolerance and it only took about 6 months. I stopped eating sugar and processed foods as well. Since I eat fermented foods on a daily basis and take mineral and vitamin supplements, I feel so much better. Knowing my body is actually absorbing these essential nutrients because of the fermented foods has been an absolute life saver. I’ve started to reset my hormones naturally without the use of prescription drugs. I follow Dr. Mercola pretty closely as I agree with a lot of what he has to say. Fermented foods are mandatory in my daily life. Most “food allergies” are the body’s inability to break down food because we lack the necessary enzymes in which to do that. Fermented foods puts those enzymes back into your body. Really, its a win-win situation. Taking probiotics can help, but nothing can come close to raw, live, whole, nutrient dense fermented foods.
Is there an affordable at home testing for vitamin and mineral testing? On a very limited budget so looking for any advice. Thank You