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Genetic Testing For Gluten Sensitivity and Celiac Disease

One of the most common questions pertaining to gluten sensitivity and celiac disease? How do I get tested? Serum blood tests and lab tests are fraught with error and inaccuracies. A number of research studies have confirmed this. Many patients have these tests performed, the results come back negative, yet they still respond to a gluten free diet. Why? Many people go on a gluten free diet and feel better despite lab results. This works great if you are an adult capable of making your own decisions, but what about children? In my clinic I see this problem frequently. The following video will explain the answer to this question and more. Additionally, this video will break down genetic testing of gluten sensitivity for you. If you have had negative biopsy or blood tests for gluten intolerance or celiac disease find out now by watching… Check out our video library here…

Genetic Testing Available Here <<<

All the best, Dr. Osborne – AKA The Gluten Free Warrrior

5 Responses

  1. Dr. Osborne is right on regarding gene testing for gluten sensitivity. The way gluten sensitivity testing is done in most medical offices is consistent with typical medical attitudes and outdated practices.

    Imagine going to a dentist for a checkup and there was a small soft spot on a tooth and the dentist said they will just watch that area. The next checkup you have a small black spot where the soft spot was and still, nothing is done. Finally 6 months later you can’t stand the pain and you go back and find the tooth is half destroyed by dental decay and the dentist says, Oh, I see you have a tooth problem – we better patch that up. You wouldn’t stand for that type of poor care.

    Such is the case with typical testing and even awareness of the types of health challenges that gluten sensitivity can cause.

    Current knowledge states:

    “Gluten sensitivity is a systemic autoimmune disease with diverse manifestations. This disorder is characterised by abnormal immunological responsiveness to ingested gluten in genetically susceptible individuals. Coeliac disease, or gluten-sensitive enteropathy, is only one aspect of a range of possible manifestations of gluten sensitivity. Although neurological manifestations in patients with established coeliac disease have been reported since 1966, it was not until 30 years later that, in some individuals, gluten sensitivity was shown to manifest solely with neurological dysfunction. Furthermore, the concept of extraintestinal presentations without enteropathy has only recently become accepted. In this Personal View, we review the range of neurological manifestations of gluten sensitivity and discuss recent advances in the diagnosis and understanding of the pathophysiological mechanisms underlying neurological dysfunction related to gluten sensitivity.”

    The Lancet Neurology, Volume 9, Issue 3, Pages 318 – 330, March 2010. (

    Get tested for GS genes by a proper lab and get started with changing your family’s health future for generations to come.

  2. I had genetic testing performed through another company.

    My results are:

    Gene Marker: DQA1
    Test Result: DQA1*06
    Risk Allele – No

    Gene Marker: DQA1
    Test Result: DQA1*03
    Risk Allele – No

    Gene Marker: DQB1
    Test Result: DQB1*03
    Risk Allele – No

    Gene Marker: DQB1
    Test Result: DQB1*04
    Risk Allele – No

    Low Risk of developing Celiac Disease.

    Should I order your kit to rule out gluten sensitivity because I have so many severe ‘Celiac’ like symptoms?

    I follow all your work, have your book and have extras to give away.

    They have helped me so much.
    Thank you for all you do.

    1. Hi Sue,
      The panel #’s you have recorded above are not complete and may be misleading. It is hard to say, because not enough information was given to you. Yes, I would recommend genetic testing specifically for gluten sensitivity.
      Love that my work has been helpful for you! Thanks for sharing!

  3. Hello Dr. Osborne…
    So, I am POSITIVE for DQ2: DQA1*05:01/05:05 &

    But I am negative for DQ8:

    Base on these ressults, I assume I am definitally sensitive to gluten, but do not have celiac? Could you provide any insight on it and if you think I should really do any more testing for NCGS or CD, or is this all I need to know?

    Thank you so much!

    1. These results mean that you are homozygous for HLA-DQ2 on both alpha1 and beta1 genes. According to research, these markers put you in a high risk category for the development of celiac. They also severely predispose you to reacting to gluten when consuming (Predisposition). In my experience, a gluten free diet, would definitely be the right move your long term health. I cannot comment on the need for additional testing. For that, I would defer you back to your treating doctor.
      Hope that helps!
      Dr. O

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