Belive me I still don't understand all of this.
So this is me – PAMI
A) Gluten Sensitivity Stool and Gene Panel Complete *Best test/best value
Fecal Anti-gliadin IgA 56 Units (Normal Range is less than 10 Units)
Fecal Anti-tissue Transglutaminase IgA 30 Units (Normal Range is less than 10 Units)
Quantitative Microscopic Fecal Fat Score Less than 300 Units (Normal Range is less than 300 Units)
Fecal Anti-casein (cow’s milk) IgA 20 Units (Normal Range is less than 10 Units)
HLA-DQB1 Molecular analysis, Allele 1 0301
HLA-DQB1 Molecular analysis, Allele 2 0601
Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)
Interpretation of Fecal Anti-gliadin IgA: Intestinal
antigliadin IgA antibody was elevated, indicating that you have active
dietary gluten sensitivity. For optimal health, resolution of symptoms
(if you have them), and prevention of small intestinal damage and
malnutrition, osteoporosis, and damage to other tissues (like nerves,
brain, joints, muscles, thyroid, pancreas, other glands, skin, liver,
spleen, among others), it is recommended that you follow a strict and
permanent gluten free diet. As gluten sensitivity is a genetic syndrome,
you may want to have your relatives screened as well.
Interpretation of Fecal Anti-tissue Transglutaminase IgA: You have an autoimmune reaction to the human enzyme tissue transglutaminase, secondary to dietary gluten sensitivity.
Interpretation of Quantitative Microscopic Fecal Fat Score: Provided
that dietary fat is being ingested, a fecal fat score less than 300
indicates there is no malabsorbed dietary fat in stool indicating that
digestion and absorption of nutrients is currently normal.
Interpretation of Fecal Anti-casein (cow’s milk) IgA: Levels of fecal IgA antibody to a food antigen greater than or equal to 10 are
indicative of an immune reaction, and hence immunologic “sensitivity” to that food.
For any elevated fecal antibody level, it is recommended to remove that food from your diet.
Values less than 10 indicate there currently is minimal or no reaction to that food and hence,
no direct evidence of food sensitivity to that specific food. However, because 1 in 500 people
cannot make IgA at all, and rarely, some people can still have clinically significant reactions
to a food antigen despite the lack of a significant antibody reaction (because the reactions
primarily involve T cells), if you have an immune syndrome or symptoms associated with food
sensitivity, it is recommended that you try a strict removal of suspect foods from your diet
for up to 12 months despite a negative test.
Interpretation Of HLA-DQ Testing: Although
you do not possess the main HLA-DQB1 genes predisposing to celiac sprue
(HLA-DQB1*0201 or HLA-DQB1*0302), HLA gene analysis reveals that you
have two copies of a gene that predisposes to gluten sensitivity (any
DQ1, DQ2 not by HLA-DQB1*0201, or DQ3 not by HLA-DQB1*0302). Having two
copies of a gluten sensitive gene means that each of your parents and
all of your children (if you have them) will possess at least one copy
of the gene. Two copies also means there is an even stronger
predisposition to gluten sensitivity than having one gene and the
resultant immunologic gluten sensitivity may be more severe. This test
was developed and its performance characteristics determined by the
American Red Cross – Northeast Division. It has not been cleared or
approved by the U.S. Food and Drug Administration.